Application

Detect Protocadherin 19 using this Anti-Protocadherin 19 Antibody validated for use in IHC (Paraffin).

Research CategoryCell Structure

Research Sub CategoryAdhesion (CAMs)

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Protocadherin 19 in mouse hypothalamus and hind brain tissues, whereas a 1:2,000 dilution from a representative lot detected Protocadherin 19 in human cerebellum tissue.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Protocadherin-19, also known as Potential calcium-dependent cell-adhesion protein (PCDH19), is a single-pass type I membrane protein that is moderately expressed in all regions of the brain and ovary, and has low expression in other tissues. Defects in PCDH19 cause epileptic encephalopathy, early infantile type 9 (EIEE9), also known as epilepsy female-restricted with mental retardation.

Immunogen

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Protocadherin 19.

Epitope: Cytoplasmic domain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Immunohistochemistry in human cerebral cortex tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Protocadherin 19 in human cerebral cortex tissue.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

126 kDa calculated